Leadless Patient Selection: TTVR and Active Infections

  • Published:  09 April 2026
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Leadless Patient Selection: TTVR and Active Infections

  • Published:  09 April 2026
  • Likes: 

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Overview

Discover the future of pacing in complex structural and high-risk patients with insights from some of the world’s leading experts.

 

Prof Aldo Rinaldi (Guy's and St Thomas’ NHS Foundation Trust, UK) and Dr Tiffany Patterson (Guy’s and St Thomas’ NHS Foundation Trust, UK) explore the latest advances in leadless pacemaker technology, with a particular focus on its role in patients undergoing Transcatheter Tricuspid Valve Replacement (TTVR) and other complex structural interventions. The series examines how leadless pacing can overcome the limitations of transvenous leads in patients with tricuspid valve disease, prior valve interventions, venous occlusion and high infection risk.

 

They are joined by Prof Eyal Nof (Sheba Medical Center, IL), who addresses one of the most challenging clinical scenarios faced by interventional teams – pacing strategies in patients with active infection and device extraction. The discussions cover patient selection, procedural planning, device implantation techniques and strategies to minimise complications in high-risk populations.

 

Through real-world case discussions and interactive Q&A, the series provides practical insight into how leadless pacing integrates into structural heart and complex intervention workflows, including peri-procedural considerations, imaging guidance, complication management and post-implant follow-up.

This video series is supported by

Learning Objectives

  • Identify the key indications and procedural advantages of leadless pacemakers in patients undergoing TTVR and other structural heart interventions
  • Understand the role of leadless pacing in patients with active infection, device extraction or limited venous access
  • Apply case-based procedural strategies for patient selection, implantation planning and complication management when using leadless pacing in complex patients

Target Audience

  • Interventional Cardiologists
  • Electrophysiologists
  • General Cardiologists
  • Other healthcare professionals involved in structural heart disease, device therapy and leadless pacing pathways

More from this programme

Part 1

Welcome and Introduction

Dr Alphons Vincent opens the webinar, shares the educational goals and provides an introduction to the topic.

Part 2

Leadless Pacemakers in Transcatheter Tricuspid Valve Repair Patients

Dr Tiffany Patterson and Prof Aldo Rinaldi review the latest evidence on cardiac implantable electronic devices (CIEDs) in the setting of transcatheter tricuspid valve repair, highlighting the advantages and considerations of leadless pacemakers.


 

Part 3

Leadless Pacemakers in Patients With Active CIED Infection

Dr Eyal Nof explores the use of leadless pacemakers in patients with active CIED infections, focusing on their clinical role, real-world experience and cost considerations.

Part 4

Questions and Answers

The faculty answer audience questions, share expert insights and participate in an interactive discussion.

Faculty Biographies

Eyal Nof

Eyal Nof

Director of Invasive Electrophysiology Service

Dr Eyal Nof is the Director of Invasive Electrophysiology Service at Sheba Medical Center, Ramat Gan, IL.

Dr Nof now primarily focuses on complex ablations, particularly VT ablations and lead extractions.

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