TCT 2025 Late-Breaking Science Collection

  • Published:  21 October 2025
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TCT 2025 Late-Breaking Science Collection

  • Published:  21 October 2025
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About the episode

NVM Cardiology Conference Reflections: What’s Hot at TCT 2025?

Join Prof Nicolas Van Mieghem, Transcatheter Interventions Online Course Director, as he breaks down the most important late-breaking trials from TCT 2025.

In this 15-minute session, he reviews eight key studies, highlighting what the new data reveal, where existing evidence deserves another look, and which findings could influence clinical practice and future guidelines.

Trials featured include: SELUTION DeNovo, OCVC-BIF, Short-CUT, VICTORY, STORM-PE, PARTNER 3 Low-Risk, ENCIRCLE, NOBLE, and PROCTOR.

Concise, insightful, and practice-focused — a must-watch ahead of one of the year’s biggest interventional data releases.

Overview

Stay Updated with Our TCT 2025 Video Coverage

We’re bringing you independent, critical insights straight from TCT 2025.

Join Prof Nicolas Van Mieghem in Cardiology Conference Perspectives as he discusses what the late-breaking data could mean for your practice.

Don’t miss our short Expert Interviews with investigators, offering concise analyses and practical take-home messages.

Hear Dr Mirvat Alasnag and Dr Rasha Al-Lamee share their views on the data they believe will have the greatest impact on clinical practice.

Follow the hot topics driving innovation in interventional cardiology, and stay tuned for fresh perspectives, real-world insights and global viewpoints, all coming soon on Transcatheter Academy.

More from this programme

Part 1

NVM Cardiology Conference Perspectives

A focused video series where Prof Nicolas Van Mieghem offers expert reflections on the most impactful late-breaking trials shaping interventional cardiology at TCT 2025.

Faculty Biographies

Nicolas M Van Mieghem

Nicolas M Van Mieghem

Medical Director

Prof Van Mieghem initially intended to train as a cardiac surgeon but decided to specialise in interventional cardiology instead, following advice from a mentor. This decision was cemented when he read the first-in-human case report of transcatheter aortic valve implantation (TAVI) in Circulation by Alain Cribier in 2002. Prof Van Mieghem believes that great cardiologist genuinely cares for their patients. He names Gary Roubin, Dr Manu Malbrain and Professor Patrick Serruys among his mentors. 

 

His current research focuses on cerebral embolic protection during TAVI and the search for improved large bore closure devices. He works actively in expanding TAVI indications, most notably TAVI as a means to further unload the left ventricle in heart failure patients with moderate aortic stenosis (the TAVR UNLOAD trial). Prof Van Mieghem is also involved in the development and dispersion of mechanical circulatory support (MCS) devices as well as transcatheter mitral…

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