TCT 2025 - The PREVUE-VALVE study finds an 8.2% prevalence of moderate or greater valvular heart disease amongst Americans age 65-85, increasing to 18.4% when participants with mild to moderate VHD were included.

Dr David J. Cohen (Cardiovascular Research Foundation & St Francis Hospital, US) joins us to discuss findings from the PREVUE-VALVE study, examining age and sex-specific prevalence of acquired valvular heart disease in Americans aged 65-85.

This cross-sectional study enrolled 2,870 participants aged 65-85 years across the United States, utilizing in-home echocardiography to reduce barriers to participation.

Key findings revealed VHD had a prevalence of 8.2% in this patient group, increasing to 18.4% when individuals with mild to moderate VHD were included. The prevalence of VHD increases with advanced age.

Interview Questions:
1. What gaps in our understanding of VHD prevalence motivated the PREVUE-VALVE study?
2. What was the study design and patient population?
3. What were your key findings presented at TCT 25?
4. How might these findings inform or change clinical practice?
5. What are the next steps for this research?

Recorded on-site at TCT 2025, San Francisco.
Editors: Jordan Rance.