NVM Cardiology Conference Reflections: What’s Hot at AHA 2025?

Join Prof Nicolas Van Mieghem, Transcatheter Interventions Online Course Director, as he shares his  perspective on the most anticipated late-breaking science from AHA 2025; the year’s defining moments in structural, coronary therapeutics.

What transformative data should we expect at this year’s meeting? Which studies will challenge existing paradigms or validate emerging strategies? And where might these insights reshape practice and influence upcoming clinical guidelines?

In just under 10 minutes, Prof Van Mieghem provides concise yet incisive commentary on key late-breaking trials, a focused, evidence-driven review designed for interventional and heart team specialists preparing for the next major wave of cardiovascular innovation.

Late-Breaking AHA 25 Trials Previewed:

00:00:35 — CLOSURE-AF: Left atrial appendage CLOSURE in patients with Atrial Fibrillation at high risk of stroke and bleeding compared to medical therapy

00:02:15 — FAVOR 4-QVAS: Angiography-derived FFR-Guided Coronary Artery Bypass Grafting for Patients undergoing Valve Surgery with Concomitant Coronary Artery Disease

00:04:42 — TOP Trial: Liberal or Restrictive Transfusion Strategy after General and Vascular Surgery: The Transfusion Trigger after Major Operations in High Cardiac Risk Patients Trial

00:05:57 — CELEBRATE: Prehospital treatment with Disaggprotm (Zalunfiban) in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention

00:08:50 — OPTIMAL: Prospective, multicenter, open-label, randomized controlled trial of deferred stenting versus prompt stenting in acute occlusion of left main coronary artery

Stay tuned for our expert coverage from AHA 2025, featuring interviews with lead investigators, deep-dive analyses from global thought leaders, and perspectives that place the latest data in real-world clinical context.

Join us for live updates from New Orleans and follow Radcliffe Cardiology for more expert reflections, case discussions, and practical takeaways from the American Heart Association’s flagship annual meeting.