NVM Cardiology Conference Reflections: What’s Hot at TCT 2025?

Join Prof Nicolas Van Mieghem, Transcatheter Interventions Online Course Director, as he shares his critical perspective on some of the key late-breaking data highlights from TCT 2025.

What should we expect from the new data? Where should we take a closer look at the existing evidence and the premise of these trials? And which results could ultimately change current practice and influence clinical guidelines?

In just 15 minutes, Prof Van Mieghem reviews eight major TCT trials; concise, insightful, and focused on the implications for interventional cardiology. Tune in and get ready for one of the most important interventional data releases of 2025.

Late-Breaking TCT 25 Trials Covered:
0:51: SELUTION DeNovo (NCT04859985): A Prospective Randomized, Multi-center, International, Single-blind, Clinical trial compared the Selution DEB strategy versus DES strategy.
2:11: OCVC-BIF: Comparison of drug-coated versus conventional balloons for the side branch of the bifurcation lesion - multicenter randomized controlled study
3:53: Short-CUT(NCT06089135): Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Trial
5:12: VICTORY (NCT05346068): The Value of IVL Compared To OPN Non-Compliant Balloons for Treatment of RefractorY Coronary Lesions Trial
5:58: STORM-PE (NCT05684796): A Prospective, Multicenter, Randomized Controlled Trial Evaluating Anticoagulation Alone vs Anticoagulation Plus Mechanical Aspiration With the Indigo® Aspiration System for the Treatment of Intermediate High Risk Acute Pulmonary Embolism
Conditions 
7:37: PARTNER 3 Low-Risk (NCT02675114): Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
10:03: ENCIRCLE (NCT04153292): SAPIEN M3 System Transcatheter Mitral Valve Replacement Via Transseptal Access
11:46: NOBLE: Coronary Artery Bypass Grafting Vs Drug Eluting Stent Percutaneous Coronary Angioplasty in the Treatment of Unprotected Left Main Stenosis
13:25: PROCTOR (NCT03805048): PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior cORonary Artery Bypass Graft Surgery

Stay tuned for our expert coverage, featuring short interviews with investigators, global perspectives, summaries of key topics in interventional cardiology, and insights into career journeys. Join us as we cover TCT 25 live from San Francisco.
More coming soon to Transcatheter Academy